It ruled the children's hospital could turn off his life support.
What is wrong with Charlie? The parents also disputed some of the hospital's findings about the severity of Charlie's brain damage, saying he was able to open his eyes in June at a picnic on the hospital's roof.
He can not open his eyes or move his arms or legs.
The disease has caused damage to the boy's brain and rendered him unable to breathe without assistance, according to the hospital, but Charlie's parents downplayed the extent of the damage on Sunday.
Charlie's father says that an American hospital has offered help so his soon undergo treatment by doctors who are specialists in Charlie's genetic condition.
Now, reports ABC News, Charlie Gard's parents are getting a bit of a reprieve.
She spoke on Monday as the case was due to return to court - the latest hearing in a protracted legal fight over whether or not he should be taken overseas for experimental treatment that his parents believe could save his life.
Under the present high court ruling, the hospital is forbidden from allowing Charlie to be transferred for nucleoside therapy anywhere. The British hospital treating a terminally ill baby boy said on July 7, 2017 it would examine claims that he could be treated after US President Donald Trump and Pope Francis drew worldwide attention to the case.
How did Charlie's doctors reach this decision?
In his ruling, Justice Nicholas Francis cited testimony from Dr I, who conceded that Charlie is unlikely to improve with the experimental therapy, but he would still treat the boy.
They want the 11-month-old to receive experimental treatment in the U.S., but doctors argue it would not help.
A judge has begun overseeing the latest round of litigation at a High Court hearing in London.
However, the hospital refuses to allow this because it says that what Charlie's parents want "would prolong Charlie's suffering" and it can't be justified.
Why is the case back in the courts?
On Monday afternoon, the case returns to the High Court to hear fresh arguments following new information from researchers at the Vatican's children's hospital.
Two global hospitals and their researchers have been in touch with GOSH with more information about nucleoside therapy - drugs created to help treat MDDS.
The wrenching case has drawn interventions from Pope Francis and U.S. President Donald Trump, who have both said they will do what they can to help.
Professor Neena Modi, president of the Royal College of Paediatrics and Child Health admitted Charlie's situation is "heartbreaking" for his parents, and "difficult" for others including medical staff, but went on to claim even well-meaning interventions from outsiders can be unhelpful.
"There's now seven doctors supporting us from all over the world - from Italy, from America, from England as well, that think that this has a chance", Yates said outside the hospital.
GOSH said on Friday it still believed that the treatment would be "futile", despite the new High Court referral.
GOSH describes experimental nucleoside therapies as "unjustified" and the treatment is not a cure.